Angelo Fierro grew up on the tough streets of Boston's Little Italy; the North End. He began to study acting when he halfheartedly took some theater electives in college. Two years later, he had already appeared in major roles in a number of films. An appearance at Stand Up New York comedy club shortly thereafter, would begin to shape his comedic bones and cement a compelling desire to continue performing. Though quite at home in any genre, villain roles seemed to be drawn to him. In 2002, he was cast in his breakthrough television role as the Russian mob boss "Vladimir," on the TV series "Ocean Ave." (2002), starring Megan Fox . He went on to act in films graced by the likes of Eva Longoria and veteran actor Peter Greene , in the movies Señorita Justice (2004) (V), and Final Engagement (2007) (V), respectively. A devotee of Stanislavski, he says, "The recreation of truth through acting and the exploration of film as an art form, remains the driving force of my life."

Had to body-check basketball stars Eddie Jones and Brian Grant repeatedly for the filming of a Miami Heat commercial.His make-up and accent on "The Michael Jackson Trial" (2005), caused many friends and family not to recognize him.Once hired to photo-double for James Gandolfini on an episode of The Sopranos and later did a TV commercial based on the Tony Soprano character.